pathology of breast cancer

Release time ：Nov-16,2024

The pathology of breast cancer is a scientific discipline that investigates the onset, progression, and biological properties of breast cancer, which plays a crucial role in diagnosis, treatment, and prognostic evaluation. Breast cancer is a complex disease with a variety of pathological subtypes, including ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC), lobular carcinoma in situ (LCIS), and invasive lobular carcinoma (ILC). These distinct pathological subtypes lead to variations in clinical presentation, therapeutic approaches, and outcomes of breast cancer.

DCIS, the most prevalent non-invasive form of breast cancer, constitutes approximately 20% of all breast cancers. Originating from the epithelial cells of the mammary ducts and confined within the ducts without breaching the basement membrane, DCIS generally has a favorable prognosis. IDC, the most common invasive form, accounts for about 80% of all breast cancers. Arising from the mammary duct epithelial cells and penetrating the basement membrane to invade surrounding tissues, IDC tends to have a poorer prognosis. LCIS, a less common subtype, represents around 5% of all breast cancers. It originates from the epithelial cells of the mammary lobules and remains confined within the lobules, thus also having a more favorable prognosis. ILC, another less common subtype, makes up about 10% of all breast cancers. Originating from the mammary lobule epithelial cells and breaching the basement membrane to invade surrounding tissues, ILC typically has a poorer prognosis.

In conclusion, the diversity of breast cancer pathological subtypes influences the clinical presentation, treatment options, and prognosis. Understanding one's specific pathological subtype is essential for breast cancer patients. Additionally, regular breast examinations for early detection, diagnosis, and treatment are vital for enhancing the cure rate of breast cancer. Throughout treatment, patients should adhere to medical advice and avoid self-medicating to ensure optimal therapeutic outcomes.