breast cancer testosterone

Release time ：Nov-10,2024

The relationship between breast cancer and testosterone is often intricate. While breast cancer is predominantly associated with estrogen levels, testosterone may also play a role in the development of breast cancer under certain conditions.

Testosterone, an androgen, is typically present in low concentrations in women. However, in specific conditions such as polycystic ovary syndrome, testosterone levels in women can rise. Research indicates that elevated testosterone levels might accelerate the proliferation of breast cells, increasing the risk of breast cancer. Furthermore, testosterone can indirectly influence breast cancer development by being converted into estrogens. This conversion is significant because testosterone can transform into estrone and estradiol, both of which are linked to the onset and progression of breast cancer.

Despite this, not all breast cancer patients are influenced by testosterone. In reality, the majority of breast cancer cases occur postmenopausally when estrogen levels have already declined, diminishing the impact of testosterone. Thus, for most patients, treatment focuses on reducing estrogen levels or inhibiting estrogen effects.

Overall, while testosterone may influence breast cancer development in some instances, its role is generally less pronounced than that of estrogens. However, this does not imply that the effects of testosterone can be disregarded, particularly in women with elevated testosterone levels. Consequently, for women with a family history of breast cancer or other risk factors, it is crucial to undergo regular breast examinations and seek medical advice on reducing the risk of breast cancer.