extranodal extension in breast cancer

Release time ：Dec-28,2024

Metastasis of breast cancer to peripheral lymph nodes refers to the dissemination of tumor cells from the primary tumor site to the adjacent lymphatic system. This occurrence is common among breast cancer patients and is significantly associated with patient prognosis.

Initially, minimal peripheral lymph node involvement may be confined to the sentinel lymph nodes, which are the first nodes to receive lymphatic drainage from the breast. At this stage, tumor cells might form only microscopic deposits within these nodes, detectable through meticulous pathological examination. Subsequently, as the disease advances, tumor cells can spread to additional lymph nodes, establishing larger metastatic lesions. These are often identified during clinical or imaging assessments. In extreme cases, tumor cells may disseminate further through the lymphatic system to distant organs, such as the lungs, liver, or bones, resulting in distant metastasis.

For individuals with breast cancer, routine medical check-ups to monitor the condition of peripheral lymph nodes are essential. Upon detection of any lymph node metastasis, prompt medical consultation and adherence to treatment recommendations from healthcare providers are imperative. Additionally, maintaining a healthy lifestyle, including a balanced diet, regular physical activity, and abstaining from smoking, can contribute to better therapeutic outcomes and overall quality of life.