ovarian suppression breast cancer

Release time ：Dec-25,2024

Ovarian suppression is a therapeutic strategy for breast cancer that halts tumor growth by reducing estrogen levels in the body. It is typically indicated for patients with hormone receptor-positive breast cancer, particularly those who have not yet reached menopause.

During the implementation of ovarian suppression, either surgical removal of the ovaries (bilateral oophorectomy) or pharmacological approaches to inhibit ovarian function may be utilized. Medical treatments may involve gonadotropin-releasing hormone analogs (GnRH analogs), which can temporarily deactivate ovarian function and decrease estrogen production. Furthermore, for postmenopausal women, aromatase inhibitors (AIs) are a common therapeutic option, as they diminish the body's capacity to convert other substances into estrogen.

It is important to recognize that while ovarian suppression can help manage certain breast cancer types, it may also lead to side effects such as intensified menopausal symptoms, including hot flashes, vaginal dryness, and a decline in bone density. Consequently, physicians consider a patient's condition, age, fertility desires, and overall health when contemplating ovarian suppression as part of a treatment regimen.

In their daily lives, breast cancer patients undergoing ovarian suppression should maintain healthy habits, such as a balanced diet, regular exercise, and stress reduction, all of which can enhance treatment outcomes and quality of life. Additionally, patients should undergo regular check-ups, monitor their health closely, and adjust their treatment plans under medical supervision.