extranodal extension breast cancer

Release time ：Dec-25,2024

Extranodal extension in breast cancer refers to the spread of cancer cells beyond the breast, potentially reaching the skin, chest wall muscles, or other organs. This condition can complicate treatment and increase the risk of recurrence, highlighting the importance of recognizing its clinical presentations and contributing factors for early detection and intervention.

Breast cancer with extranodal extension might present with skin alterations, such as dimples, an orange-peel texture, or erythema and swelling. The tumor could also infiltrate the chest wall muscles, leading to chest pain or tenderness. Moreover, breast cancer cells can metastasize to distant organs like the lungs, bones, or liver via the bloodstream or lymphatic system, causing organ-specific dysfunction and symptoms. It's important to note that not all breast cancer patients will develop extranodal extension, and its occurrence varies among individuals.

Regular self-examinations and professional screenings are advised for early identification of extranodal extension in breast cancer. If suspicious signs are detected, immediate medical consultation is essential for professional evaluation and treatment. Treatment strategies are tailored to the patient's unique circumstances and may encompass surgery, radiotherapy, chemotherapy, and other modalities. Patients are urged to adhere to their physicians' instructions throughout the treatment process and avoid making unilateral adjustments or discontinuing therapy without guidance.