invitae hereditary breast cancer stat panel

Release time ：Dec-22,2024

The Hereditary Breast Cancer Statistical Panel is a diagnostic tool designed to evaluate whether individuals possess genetic mutations linked to an increased risk of breast cancer. This panel commonly tests for the BRCA1 and BRCA2 genes, along with other genes associated with breast cancer risk. By detecting these genetic alterations, physicians can more accurately assess a patient's susceptibility to breast cancer and offer tailored preventative and therapeutic approaches.

Within the Hereditary Breast Cancer Statistical Panel, BRCA1 and BRCA2 mutations are the most prevalent. These mutations substantially raise the risk of breast and ovarian cancers in women, as well as the risk of breast cancer in men. Beyond BRCA1 and BRCA2, there are additional genes, such as TP53, PTEN, and STK11, that may also be implicated in heightened breast cancer risk. Although mutations in these genes are less common, their potential impact on breast cancer risk can be more significant.

For individuals with a family history or other high-risk indicators, undergoing the Hereditary Breast Cancer Statistical Panel can provide insight into their personal risk profile and inform appropriate preventative actions. This may encompass more frequent screenings, lifestyle modifications, and in certain instances, prophylactic surgery. However, such decisions should be made in consultation with a healthcare provider, given the unique circumstances of each case.