serd breast cancer

Release time ：Dec-16,2024

SERD (Selective Estrogen Receptor Degraders) breast cancer is a distinct subtype of breast cancer that typically shows a favorable response to endocrine therapy. This subtype of breast cancer cells harbors estrogen receptors (SER), allowing for the inhibition of tumor growth through drugs that target these receptors. However, for individuals with SERD breast cancer, the treatment options and prognosis can be influenced by multiple factors.

Initially, for early-stage SERD breast cancer, surgery is often the treatment of choice, with the goal of removing the tumor tissue. Following surgery, based on the patient's specific circumstances, additional treatments such as radiation therapy, chemotherapy, or endocrine therapy may be necessary. Endocrine therapy is primarily indicated for patients with estrogen receptor-positive breast cancer and works by blocking the effects of estrogen or reducing estrogen levels in the body to inhibit tumor growth. Commonly utilized endocrine therapy medications include tamoxifen and aromatase inhibitors.

For patients with advanced or metastatic SERD breast cancer, the objectives of treatment are to control disease progression, alleviate symptoms, and enhance the quality of life. In these cases, a combination of various therapeutic approaches may be employed, such as chemotherapy, targeted therapy, and endocrine therapy. Moreover, for certain types of SERD breast cancer, such as HER2-positive breast cancer, targeted therapies that act on the HER2 protein are also available.

Regular follow-up and monitoring are crucial for SERD breast cancer patients to promptly detect any signs of recurrence or metastasis. Additionally, patients should maintain healthy lifestyle practices, including smoking cessation, alcohol moderation, a balanced diet, and regular physical activity, to reduce the risk of recurrence and improve survival quality. Throughout the treatment process, patients should closely monitor their health and seek medical attention promptly if they experience discomfort or have concerns, consulting with healthcare professionals for guidance.